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In patients with confirmed COVID-19, ELISA detection of IgM antibodies had a sensitivity of 77.3% and specificity of 100%. For IgG the test had a sensitivity of 88.3% and specificity of 95%. The gold standard utilized was RT-PCR. Comment: Keep in mind that RT-PCR doesn't have a perfect sensitivity and specificity, thus, the sensitivity of antibody testing is a rough estimate. Clin Infect Dis. 2020 Apr 19. pii: ciaa461. doi: 10.1093/cid/ciaa461.    (retrieved Apr, 2020). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.