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Enhanced glucose control significantly prevents the development of clinical neuropathy and reduces nerve conduction and vibration threshold abnormalities in type 1 diabetes mellitus, and to a lesser extent in type 2 diabetes. However, enhanced glucose control also significantly increases the risk of severe hypoglycemic episodes. Cochrane Database of Systematic Reviews 2012, Issue 6. Art. No.: CD007543.    (retrieved Jun, 2012). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.