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Extremely dense breasts and first degree relatives with breast cancer were each associated with at least a 2 fold increase in risk for breast cancer in women aged 40 to 49 years. Ann Intern Med. 2012 May 1;156(9):635-48.    (retrieved May, 2012). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.