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This review looks at some of the mechanisms by which aspirin is chemoprotective against colorectal cancer. The effect may be due to persistent COX-1 inhibition in platelets and transient COX-1 and/or COX-2 inhibition in nucleated cells. World J Gastrointest Pharmacol Ther. 2014 Feb 6;5(1):40-49.    (retrieved Apr, 2014). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.