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This randomized placebo controlled study of 120 computer users found that blue blocking lenses did not reduce signs or symptoms of eye strain resulting from extended screen time. Comment: This study is interesting, but incomplete. What it lacks is a comparison of wearing no glasses versus wearing glasses (blue blockers or plain clear glasses). The researchers had the opportunity to evaluate whether or not the placebo effect of wearing glasses reduced the eye strain of extended screen time. Am J Ophthalmol . 2021 Jun;226:243-251. doi: 10.1016/j.ajo.2021.02.010    (retrieved Oct, 2021). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.