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Statins cost-effective for the primary prevention of cardiovascular disease (preventing a first event). Cochrane Database of Systematic Reviews 2013, Issue 1. Art. No.: CD004816.    (retrieved Mar, 2013). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.