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Nicotine replacement, bupropion, or varenicline approximately double the odds of success when attempting to stop smoking. Nicotine replacement is best when a long-acting nicotine patch is combined with a short acting product such as nicotine lozenges, gum, inhalers, or nasal sprays. It can be helpful to extend treatment beyond 12 weeks. Counseling, including telephone quit lines, also helps increase the quit rate. JAMA. 2012 Oct 17;308(15):1573-80    (retrieved Oct, 2012). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.