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Coronary artery calcium volume appears to be positively associated with an increased risk of coronary heart disease and cardiovascular disease. Coronary artery calcium density, however, is inversely associated with CHD and CVD. Comment: A higher coronary artery calcium volume increases risk, whereas a higher coronary artery calcium density decreases risk. JAMA. 2014 Jan 15;311(3):271-8.    (retrieved Apr, 2014). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.