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Positive trials of tPA for ischemic stroke are cited more often than neutral trials or negative trials. Comment: This study found that there is a significant amount of CITATION BIAS in the use of tPA in ischemic stroke. Perhaps this is because we always want to do something, like give a fancy drug or call a Code Stroke, rather than just stand by and give aspirin or clopidogrel. This citation bias may have disasterous results, so must be strongly guarded against. Trials. 2016;17(1):473    (retrieved Sep, 2016). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.