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This study found that twice daily aspirin was superior to once daily aspirin in overall antiplatelet effect as measured by serum thromboxane B2. Comment: This study did not find a clinical benefit, however, it suggests that twice daily aspirin instead of once a day may be preferred. Note that the total daily dose can be the same, but giving half in the morning and half at night likely is superior to giving the whole dose just once a day. Am J Cardiovasc Drugs. 2020 May 11    (retrieved May, 2020). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.