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This study found that probiotics were not helpful in the treatment of infantile colic. Comment: The cause of infantile colic is not well understood. Whether or not it is due to a gastrointestinal abnormality is not known. There is no single effective treatment for colic known, and in general most clinical guidelines recommend reassurance and supportive care. BMJ. 2014 Apr 1;348:g2107    (retrieved Apr, 2014). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.