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This meta-analysis found that 1-2 alcoholic drinks per day for women and 2-4 per day for men was inversely associated with a 15% to 20% reduction in total mortality. A J-shaped relationship between alcohol intake and mortality was found in both men and women. This analysis looked at 34 studies including a total of over 1 million subjects and 95k deaths. Comment: Whether or not mild alcohol intake decreases premature death remains unclear, however, this study suggests a possible benefit. What is clear is that binge drinking or daily intake in excess about 2 drinks a day is associated with increased health risks. Arch Intern Med . 2006 Dec 11-25;166(22):2437-45.    (retrieved Sep, 2022). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.