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Aspirin appears to reduce the risk of cancer with distant metastasis by about 30%. There is some evidence that aspirin may decrease the risk of metastases in patients with adenocarcinoma. Aspirin may be particularly helpful in smokers. A low-dose, slow-release formulation of aspirin designed to inhibit platelets but to have little systemic bioavailability was found to be as effective as higher doses. Lancet. 2012 Apr 28;379(9826):1591-601.    (retrieved May, 2012). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.