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The pneumococcal vaccine in South Africa substantially decreased the rate of invasive pneumococcal disease among children. Rates decreased by about 70%. Comment: Vaccinations work. N Engl J Med. 2014 Nov 13;371(20):1889-1899. Epub 2014 Nov 11.    (retrieved Nov, 2014). There are currently 1090 pearls in the database. While every attempt has been made to ensure accuracy, mistakes can and do occur. Use databank at your own risk. All pearls © 2024 by the Internet Medical Association. Click Here to view more medical pearls.